Endocrine Abstracts

Introduction: We report the case of a patient with corticotropic insufficiency associated with diabetes insipidus who presented to the emergency room with profound hyponatremia; a complicated situation, whose solution was hidden in the galenic form of Desmopressin.Case report: Mrs Y. Amina, 37 years old, has been followed for 10 years for a non Langerhansian histiocytosis of pituitary location, complicated by a corticotropic insufficiency under hydrocort...

Introduction: Pituitary apoplexy is an acute infarction and/or hemorrhage of the normal or tumoral pituitary gland. It is a rare mode of revelation of pituitary adenomas, and the only situation where the pituitary adenoma can be complicated by a diabetes insipidus. Case report: Mrs Amina. Y, 54 years old, has been followed for 8 years for diabetes mellitus treated with metformin, and dyslipidemia under statins, presents in consultation for a severe polyu...

Introduction: Enzyme block is a rare disorder that can be discovered at birth by a severe, life-threatening disorder or in a more attenuated form in adulthood by a clinical picture of hyperandrogenism most often. The enzyme block most commonly suspected in high blood pressure is 11 B OH blockWe report the case of a young patient who was diagnosed with 21 hydroxylase enzyme block by secondary hypertension testing.Observation: This is a 32 year old patient...

Background: Graves’ disease (GD) is the commonest cause of primary hyperthyroidism in iodine-sufficient areas. First-line treatment is a 12-18 month course of anti-thyroid drugs (ATD). However, around 50% of GD patients will relapse, requiring further assessment and definitive treatment with radioactive iodine or thyroidectomy. Identifying risk factors that predict relapse or treatment failure after stopping ATD is important in guiding management. Several risk factors hav...

Introduction: Adrenal tumors are commonly discovered incidentally on cross-sectional abdominal imaging. The Incidence of adrenal tumors increased 10-fold in the past 2 decades, with most diagnosed in older adults. In any patient with a newly discovered adrenal mass, determining whether it is functioning adenoma or non-functioning and identifying whether it is ACTH dependent or not is crucial to avoid missing the real underlying pathology.Clinical case: A...

Case history: A 20-year-old male presented with a one-year history of reduced libido, headache and slowly progressive blindness. His symptoms (particularly the visual deterioration) had a great impact on his daily life, leading to dismissal from work. Examination showed decreased visual acuity (12/6 bilaterally), reduced colour vision and a dense bitemporal visual field loss. Testes measured 15 mls bilaterally. He had no clinical stigmata of acromegaly, nor Cushing’s dise...

Introduction: In the UK, the fasting plasma concentrations of a panel of gut hormones (vasoactive intestinal peptide (VIP), gastrin, pancreatic polypeptide, glucagon and somatostatin as well as chromogranin A) are frequently measured during the evaluation of patients who have confirmed or clinically suspected neuroendocrine tumours (NETs). However, elevated concentrations of these hormones are sometimes also detected in patients who have no other evidence of a NET. We sought t...

44 years old lady was referred to Endocrinology Clinic with history of secondary amenorrhea and hyperprolactinaemia (7800), that responded to Cabergolin treatment, which was discontinued after 2 months due to side effects (headaches). There was no galactorrhea or visual field defects. MRI Pituitary initially reported as Empty Sella. Her prolactin levels rose further along with headach after she discontinued Cabergoline (and refused alternatives). She eventually agreed for nigh...

Introduction: Radioactive iodine (RAI) is an effective and widely used treatment for thyrotoxicosis. Post-radioiodine thyrotoxicosis is a well-known side effect of RAI. This is usually mild and easily controlled mostly with beta blockers but sometimes needs anti-thyroid drugs (ATD).Aim of the study: To assess the incidence and predictors of post-radioiodine thyrotoxicosis.Methods: Retrospective analysis of 86 patients who had RAI t...

Objective: Pituitary stalk interruption syndrome (PSIS) is a rare congenital abnormality of the pituitary that is responsible for multiple anterior pituitary hormone deficiencies with the estimated incidence of 0. 5/100,000 live births. We report the a case of PSIS from Saudi Arabia.Case report: A 16 year old Saudi boy with short stature and undescended testis, status post bilateral orchidopexy presented to our endocrine clinic. He was delivered by caesa...